| Appalachian Region Interstate Compact | 2007 |
| Appalachian States Low-Level Radioactive Waste Compact | 1985 |
| Audiology and Speech Language Pathology Interstate Compact | 2020 |
| Compact for Education | 1967 |
| Compact on Mental Health | 1957 |
| Counseling Compact | 2022 |
| Driver License Compact | 1972 |
| Emergency Management Assistance Compact | 1996 |
| Emergency Medical Services Personnel Licensure Compact | 2020 |
| Interstate Agreement on Detainers | 1971 |
| Interstate Agreement on Qualifications of Educational Personnel | 1969 |
| Interstate Compact for Adult Offender Supervision | 2008 |
| Interstate Compact for Juveniles | 1963 |
| Interstate Compact for School Psychologists | 2024 |
| Interstate Compact on Adoption and Medical Assistance | 1986 |
| Interstate Compact on Educational Opportunity for Military Children | 2011 |
| Interstate Compact on Licensure of Participants in Horse Racing with Pari-Mutuel Wagering | 2000 |
| Interstate Compact on Mentally Disordered Offenders | 1970 |
| Interstate Compact on the Placement of Children | 1975 |
| Interstate Compact to Conserve Oil and Gas | 1945 |
| Interstate Insurance Product Regulation Compact | 2004 |
| Interstate Library Compact | 1972 |
| Interstate Medical Licensure Compact | 2015 |
| Interstate Mining Compact | 1972 |
| Jennings Randolph Lake Project Compact | 1994 |
| Middle Atlantic Forest Fire Protection Compact | 1967 |
| Multistate Lottery Agreement | 1988 |
| National Crime Prevention and Privacy Compact | 2006 |
| Nonresident Violator Compact | 1978 |
| Nurse Licensure Compact | 2017 |
| Occupational Therapy Licensure Compact | 2022 |
| Ohio River Valley Water Sanitation Compact | 1939 |
| PA Licensure Compact | 2024 |
| Pennsylvania-West Virginia Boundary of 1887 | 1887 |
| Physical Therapy Licensure Compact | 2018 |
| Potomac Highlands Airport Authority Compact | 1990 |
| Potomac River Basin Interstate Compact | 1961 |
| Psychology Interjurisdictional Compact | 2021 |
| Southeastern Forest Fire Protection Compact | 1955 |
| Southern Dairy Compact | 1998 |
| Southern Growth Policies Compact | 1989 |
| Southern Regional Education Compact | 1956 |
| Southern States Energy Compact | 1964 |
| State Authorization Reciprocity Agreement | 2014 |
| Streamlined Sales Tax Agreement | 2005 |
| Uniform Unclaimed Property Act | 1966 |
| Virginia and West Virginia Boundary Agreement of 1863 | 1863 |
| Virginia and West Virginia Boundary Compact of 1959 | 1959 |
| Virginia and West Virginia Boundary Compact of 1998 | 1998 |
| Virginia-West Virginia Boundary Agreement of 1866 (expansion of W. Va.) | 1863 |
| Wheeling Creek Watershed Protection and Flood Prevention District Compact | 1967 |
| Wildlife Violator Compact | 1990 |